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September 12, 2014
NIH awards aim to improve understanding of cell pathways, development of new therapies
Building on a successful three-year pilot project, the National Institutes of Health has awarded more than $64 million to six research institutions to create a database of human cellular responses, the Library of Integrated Network-based Cellular Signatures (LINCS).  Discovering such cell responses will improve scientists’ understanding of cell pathways and aid in the development of new therapies for many diseases.

September 9, 2014
NIH-convened panel recommends expanded adoption of drug and transfusion treatments for individuals with sickle cell disease
An expert panel has recommended expanded adoption of the drug hydroxyurea for the care of people with sickle cell disease, according to a report issued today. The report also suggests that clinicians give periodic blood transfusions to children with the disease to reduce stroke risk. According to the panel, both treatments are underutilized.

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Spotlight On Research

Featured Fact Sheet

images of the reduction in blood flow after a mental stress test compared to after a physical stress test and at rest

Emotional stress and heart disease in women: an interview with Dr. Viola Vaccarino
When it comes to the effects of emotional stress on the heart, young men and women may not be created equal. Understanding the role of emotional factors—in particular psychological stress—on heart disease risk is a professional passion for longtime NHLBI grantee, Dr. Viola Vaccarino, a leader in women’s health research. Read full fact sheet...


NHLBI In The News rss feed

October 2, 2014 : Brown University News
Hypertension risk rises closer to major roadways
David Orenstein
A new study in the Journal of the American Heart Association reports a significant association between living near a major roadway and the risk of high blood pressure. The Brown University-led analysis used data from NHLBI's Women's Health Initiative and assessed 5,400 post-menopausal women in the San Diego metropolitan area. Researchers found that women who lived within 100 meters of a highway or major arterial road had a 22-percent greater risk of hypertension than women who lived at least 1,000 meters away. In a range of intermediate distances, hypertension risk rose with proximity to the roadways.

October 1, 2014 : HealthDay News
Genes May Make Some More Prone to Heart Disease When Under Stress
Robert Preidt
Genes may interact with stress to trigger heart disease in some people, a new study suggests. The genetic risk occurs in about 13 percent of people, but only in those who are white. The finding could help these people reduce their heart disease risk through simple measures such as exercise, a healthy diet and stress management, the Duke University researchers said. This research was funded in part by the NHLBI.

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Director's Message
Researcher Brings Medicine One Step Closer to Widely Available Cure for Sickle Cell Disease

Gary H. Gibbons
September 2, 2014

From the use of antibiotics to prevent and treat infections in children with sickle cell disease to the FDA approval of the drug hydroxyurea, researchers have made steady progress during the last few decades in improving the lives of individuals with sickle cell disease. Yet still, a widely available cure has remained just out of reach. Now, work from a team of researchers at the National Institutes of Health, including NHLBI’s Dr. John Tisdale may open the door to reversing sickle cell disease in more patients....
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