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NHLBI Small Business Program


The NHLBI Small Business Program enables US-owned and operated small businesses to engage in research and development on innovative and commercially promising products and services to prevent, diagnose, and treat heart, lung, and blood-related diseases and disorders.

Funding for small business research is available through the Small Business Innovation Research (SBIR) and Small Business Technology Transfer (STTR) mechanisms. For an overview of these mechanisms, please visit ABOUT THE PROGRAMS. You can also explore current NHLBI SBIR/STTR funding opportunities here.

Staff from the NHLBI Office of Translational Alliances and Coordination (OTAC), are available to advise and mentor NHLBI SBIR/STTR applicants and awardees on matters relating to product development, regulatory affairs, intellectual property, product commercialization, licensing, and strategic partnerships.

We strongly encourage prospective SBIR/STTR applicants to contact us to discuss their planned funding proposals. Please visit OTAC’s website to learn more about the services that our office offers.

Latest Announcements

FY2017 SBIR Contract Topics – Proposals Due October 21

NHLBI is seeking innovative technologies that fit five topics identified in PHS2017-1: remote/mobile/wireless technology for aging in place (topic 098); ability to create inhaled peptide formulation (topic 099); MRI myocardial needle chemoablation catheter (topic 100); membranous ventricular septal defect (pmVSD) transcatheter occluder system (topic 101); and a transcatheter occluder device for paravalvular leaks (topic 102). Join the webinarexternal disclaimer on August 24, 2016 to learn more about the contract proposal process and topics at NIH and CDC. Read more about the NHLBI contract topics.

Get Tips on Your Commercialization Plan and Regulatory Strategy

Watch the NHLBI Small Biz Hangouts. Check out archived presentationsexternal disclaimer

Archives of What's New

Last Updated August 2016

Connect with Us!

Tel: 301-496-2149

Inquiry Form:
NHLBI Small Biz Inquiry Form

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Upcoming Events

10/17 AdvaMed 2016 external disclaimer - Minneapolis, MN 

10/18BIO Investor Forum external disclaimer - San Francisco, CA 

11/1NHLBI Innovation Conference - New York, NY 

11/1 - 11/3SSTi 2016 Annual Conference external disclaimer - Columbus, OH 

11/2 - 11/3Life Sciences Summitexternal disclaimer - New York, NY 

11/13 - 11/15Partnering for Cures external disclaimer - New York, NY 

11/15 - 11/17 18th Annual HHS SBIR/STTR Conference external disclaimer - Orlando, FL 



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